Clinical documentation

A selection of recommended references for the Restylane range follows:

  • Consensus recommendations for soft-tissue augmentation with nonanimal stabilized hyaluronic acid (Restylane). Matarasso SL, Carruthers JD, Jewell ML, Restylane Consensus Group. Plast Reconstr Surg. 2006;117(3 Suppl):3S-34S; discussion 35S-43S
  • The first clinical study using a new biodegradable implant for the treatment of lips, wrinkles, and folds. Olenius M. Aesth Plast Surg 1998;22:97-10
  • Injectable hyaluronic acid gel for soft tissue augmentation. A clinical and histological study. Duranti F, Salti G, Bovani B, Calandra M, Rosati M. Dermatol Surg 1998;24(12)1317-25
  • A randomised, double-blind multicenter comparison of the efficacy and tolerability of Restylane® versus Zyplast® for the correction of nasolabial folds. Narins RS, Brandt F, Leyden J, Lorenc P, Rubin M, Smith S. Dermatol Surg 2003; 29(6): 588-95
  • A randomized, evaluator-blind, multicenter comparison of the efficacy and tolerability of Perlane® versus Zyplast®  in the correction of nasolabial folds. Lindqvist C, Tveten S, Bondevik BE, Fagrell D. Plast Reconstr Surg. 2005 Jan;115(1):282-9 
  • A randomized, double-blind comparison of the efficacy of two hyaluronic acid derivatives, RESTYLANE Perlane and Hylaform® , in the treatment of nasolabial folds.Carruthers A, Carey W, De Lorenzi C, Remington K, Schacthter D, Shapra S. Dermatol Surg 2005; 31(11)Part2:1591-1598
  • A multicenter study of the efficacy and safety of subcutaneous Restylane® in aesthetic facial contouring: an interim report. De Lorenzi C, Swift A, Solish N, Weinberg M Dermatol Surg 2006; 32(2):208-215
  • The long-term efficacy and safety of a subcutaneously injected large-particle stabilized hyaluronic acid-based gel of nonanimal origin in esthetic facial contouring. DeLorenzi C, Weinberg M, Solish N, Swift A. Dermatol Surg. 2009; 35 Suppl 1:313-21
  • Injectable hyaluronic acid implant for malar and mental enhancement. Lowe NJ, Grover R Dermatol Surg 2006;32:881-5
  • Rejuvenating influence of a stabilized hyaluronic acid-based gel of non-animal origin on facial skin aging. Kerscher M, Bayrhammer J, Reuther T. Dermatol Surg 2008; 34(5): 720-6
  • Safety data of injectable nonanimal stabilized hyaluronic acid gel for soft tissue augmentation. Friedman PM, Mafong EA, Kauvar ANB, Geronemus RG Dermatol Surg 2002; 28(6): 491–4   
  • Immunogenicity studies of cosmetically administered nonanimal-stabilized hyaluronic acid particles. Hamilton RG, ABMLI D, Strobos J, Adkinson N. Dermatol Surg 2007;33:S176–S185
  • Persistence and improvement of nasolabial fold correction with nonanimal-stabilized hyaluronic acid 100,000 gel particles/mL filler on two retreatment schedules: results up to 18 months on two retreatment schedules. Narins RS, Dayan SH, Brandt F, Baldwin EK. Dermatol Surg 2008;34:S2-8